Epub Feb Progestins and progesterone in hormone replacement therapy and the risk of breast cancer. J Steroid Biochem Mol Biol. Progesterone vs.
Syst Rev. Published Jul The impact of micronized progesterone on breast cancer risk: a systematic review. Subscribe to our newsletter and stay up to date with our latest insights coming straight to your inbox:. First Name. Email Address. Progesterone and Progestins. Is there a difference between progestins and progesterone? Recent research suggests there might be. Progesterone v. Below is a graphic we created based on our research of the correct terminology.
Molecular structures differ: progestins are not the same as progesterone Progestins are a class of drugs manufactured in a lab by pharmaceutical companies to act like the progesterone our bodies make. Steroids 76 — 3. I am experiencing new constipation. I am experiencing more nausea. My one precaution might be around the testosterone. See my blog post about testosterone and weight gain. While I was on Mirena a lab draw revealed zero Testosterone.
I told my Gyne that today when she switched me from Mirena to a progestin only bc Sylind. Those symptoms are made worse by testosterone. Thank you! Yes I have the back and chest acne but it was present prior to starting testosterone. My provider felt it was possibly present due to the fact that I had zero testosterone which then was mimicking a high testosterone level due to the body attempting to right itself.
That was her opinion — my primary provider. Hi Lara your site in fantastic resource. I currently take one pump of estrogen gel and mg of utrogestan a day.
Is mg utrogestan too much. Was thinking about halving this.. I stopped almost 2 years ago and they put me on progesterone mg every day and said to use the cream also. My periods have gotten worse over the two years but the biggest problem is my hair is severely thinning.
Is it wise to take mg of progesterone daily for so long? Is it damaging my hair? Hi Lara, Thank you for clarifying these details, the information on the web is so confusing!
I am 48 and pre menopausal. I started the Pro in early August and have had several cycles and the symptoms of congestion have improved to make me functional but not always comfortable. How exactly does the progesterone help PCS? On continuous mg progesterone I will still ovulate right? But I will stop getting my period? How does that work? I can see you have written about most contraception but not this particular one and I wanted to hear your thoughts on it. I was told by the doctor all it does is thins your uterus lining so an egg can service in there.
But that you still ovulate and have a period. Which to be sounds really harmless but I am still skeptical. I want to ovulate and I want to still have my period as soon as I get off it.
In my view, the hormonal IUDs including Kyleena, Mirena, Skyla etc are better than other types of hormonal birth control. See my blog post The pros and cons of the hormonal IUD. I just wanted to say thank you so much for your book. I learned so much from it, and it gave me the confidence I needed to quit BC for good, earlier this year in quarantine.
My crippling anxiety and depression has mostly subsided, my scary bout of optic neuritis has mostly gone away, and I feel more like myself again. I do have one question though. I am about to start taking progesterone via Utrogestan, recommended by a doctor from US, close to family I live in Europe because of a menopause, I am 46 years old.
My concern is in regards of my fear of future breast cancer…or any cancer. No family history by the way, just my thoughts. Please, can you give me your advice! I am in Europe, Bulgaria and taking hormones is not very common thing specially for menopause.
Thanks in advance!!! I have been tracking my temperatures using a LadyComp. At first it seemed like things clicked back into gear pretty quickly.
I ovulated on day 19 or 20 of my pill bleed cycle and then had a short luteal phase 8 or 9 days and then had a period for about 5 days with 3 days of spotting at the end. Would it be okay to take a tablespoon of flax seeds each day, grind them up and eat them with my food? I eat a pretty clean diet. I avoid gluten and dairy for the most part and cook the majority of our food at home, largely from scratch. I eat very little processed sugar and avoid industrialized oils. I also take magnesium, B6 and other supplements.
I have your book and have read part of it but not finished it yet. I am in early menopause and trying to conceive as l also did before while being on early menopause and with the help of Vitex. I would like to have another child and I am on estradiol patches 50mcg and progesterone for 12 days x mgs. After finding out that progesterone could inhibit ovulation, l now want to either stop the body identical hormone therapy and be back to Vitex only or find a solution where l can get less progesterone whilst on oestrogen patch.
Is mgs x 12 days okay or will it also suppress ovulation? Another question is how can l have 20mg of natural progesterone as they all come in or mg capsules? Thank you so much.
But unfortunately there is no small dose when it comes to micronised progesterone, only the progestins come in small doses. Can this be achieved with vitex perhaps? Hi Lara, can vaginal micronised progesterone be used half dose as it gets absorbed better and internally? Thanks for your help Lara.
Any help will be really appreciated. I was going to ask the same, well not the cream. My sister is on a progesterone only pill due to her Diabetes type 1 for contraception. Can she take natural micronised progesterone instead? As I assume it is the thinning of the lining that is being the contraceptive?? Sorry I know the pill she is on Ceravette actually inhibits ovulation and increases viscosity of the cervical mucus. But thoughts on if there is a safer progesterone to use for contraception would be great!
My doctor just prescribed both Prometrium take at night and Provera to take in the day. I am a bit nervous about the Provera. Do you have any thoughts on this prescription? If she has prescribed Provera as well as Prometrium, it could be for an issue like hyperplasia?
I have been taking compounded natural progesterone for a long time but now apparently have to move to Prometrium. In the US, Prometrium is suspended in peanut oil. Check with your pharmacist. My Dr. I have natural progesterone cream from wild yam root.
Is taking 20mg twice a day for 5 days a high enough dose to get a bleed? I had lap excision for endometriosis Jan I was prescribed dienogest — Visanne to be taken daily until menopause I am currently Is it possible for natural progesterone to be effective for preventing return of endometriomas? I am terrified to be in endo pain again surgery changed my life amazingly , but I am equally terrified to be in this pill for years.
Ridiculous breast pain, zero libido, new mood and anxiety issues that come and go, etc. Very good to know about the differences.
I was on the combined pill but then put on the mini pill due to migraines with aura. I was taking Cilest which had mcg of progestin and 3mcg of estradiol and it was the perfect ratio for me as it kept so much under control.
I also wondered if I could take the mini pill and progesterone cream together so I can have the benefits of both ie contraception and the benefits of bioidentical progesterone? Oops, when I mentioned the ingredients of Cilest I had meant that it had 35mcg of estradiol, not 3mcg!!!! Sorry, I forgot to mention that I have Hashimotos thyroid disease too and have been on medication for that since I think the thyroid thing has been driven by the high stress and low progesterone though!
Is it possible to take more than that dose? I also take mg magnesium glycinate, 30 mg zinc, and just added turmeric. Hello, I have been taking cyclic compounded progesterone for a couple of months now. My husband is waiting on his vasectomy so we are using non hormonal birth control such as condoms until he gets it done and is cleared. We have a vacation coming up next month and he asks if it would hurt for me to take the mini pill for one month and then return to my 14on 14 off compounded progesterone the following month.
Would that cause me any serious health concerns? I have several months supply of the minipill left over after my last baby. Any advice would be great as I am not finding any information online.
Read your book and thought it was life changing. Question: Why can pharmaceutical companies not put real progesterone in the pill if it exists instead of making a similar but different version? Natural or micronized progesterone is now being prescribed more frequently by conventional doctors.
Hi Dr. He prescribed me Prometrium, but after doing some research it appears the pharmacy gave me a generic form made by the company Teva. From my research, it appears this compound is a progestin, even though it says progesterone on the label. I cannot tolerate synthetic progestins learned the hard way after a horrible reaction to HBC and am really nervous about moving forward with Prometrium after reading about the Teva form being so falsely marketed.
I would appreciate any insight you may have on which manufacturers in the US are offering the pure form of progesterone without synthetics or dangerous fillers. I am only in my 20s and am trying to be very conscious of my long-term health as I decide how to address my hormone imbalance. Feel free to contact via email if it is easier for you.
This is all so confusing. No troubles with that since on the continuous bc but hair loss is a problem- take Spiro mg for that- not sure it helps. Dr says change to Aygestin which they say is progesterone. Is that a good idea? Im not sure whether to take it or not.
Everything i read is conflicting. Real progesterone also called micronized progesterone or the brand names Prometrium or Utrogestan can also be helpful for endometriosis symptoms and does not cause hair loss.
Taking micronized progesterone actually exacerbated my endo symptoms but did help control my heavy bleeding. A endo excision specialist out of Dallas Texas Dr Dulemba actually says he tends to see that with younger women who have more aggressive forms of endo…where progesterone though me probably actually means progestin actually exacerbates symptoms.
Progestins are different molecules. Blood levels are Estrogen Progesterone 1. How do you feel About this level and ratio? Age Are you still cycling or are you postmenopausal? I am not menopausal. Taking mg progesterone. But not sure what day in my cycle because I have no uterus. Recently had one ovary removed so that could explain low levels and symptoms. Anyway she recently had the Mirena IUD put in and had her first days of feeling normal in about 15 years.
No exhaustion. Levonorgestrel does potentially inhibit or compete with progesterone. Which, in this case, could be a beneficial effect… If your girlfriend was very sensitive to the neurological effects of progesterone. Was it all the time or only premenstrually? Thanks for getting back to me. The exhaustion has been constant since approximately her early teens. She could easily sleep 12 hours a day and still be completely exhausted.
This is one of the primary research areas for Idiopathic Hypersomnia and Narcolepsy. This study seems to agree with your first point. A hypersensitivity to ALLO could have been in her problem, but in that case, the symptoms would have been restricted to the luteal post-ovulation phase which is the last two weeks of the cycle.
Because we only make ALLO after ovulation. Pretty much any progestin will shut down ALLO. The problem is that many progestins have their own negative effects on the mood and nervous system. Maybe just enough to suppress ovulation but not so much as to cause side effects.
Hi, just discovered your blog which is amazing. I have had several uterine polyps removed in the past and my periods are regular but very heavy.
Does it mean a new polyp formed? I did a scan and my Dr could not see any polyp but he also said that they can be hard to see…. Is there any solution to my pain? Thanks Lara. I did read those, and my Dr says I do not have endometriosis nor adenomyosis, my Dr says it is all due to a thick uterine layer from estrogen dominance.
Keep looking for someone that does. It discusses the problem of anovulatory cycles estrogen dominance and thickened uterine lining. Micronised bioidentical progesterone can be obtained as the brands Prometrium, Utrogestan, or compounded capsules. Amazing, here I am worrying that having come off the Merina that my body will miss all the progesterone!!!
I think its a disgrace that we are not more informed about what we put in our bodies… thank you for this information. Makes me dizzy and feel a little anxious and depressed. Is this common and any other suggestions. I took a natural compound for 6 months and felt amazing. We always assumed it was due to long-term use of birth control, which I stopped. There were some life stressors, but I swore it was another imbalance, and yet, all came back normal.
Again and again. One was the 13th day of my cycle, and one was the 18th after ovulation. Hi Lara! Thanks to you and your book I started to understand better my specifics and after 3 months BBT charting and testing progesterone 7 days after ovulation it seems I do have a progesterone deficiency.
So I need to start supplementing progesterone, but in Europe is hard to find natural progesterone. Its interesting that for both progestins and progesterone are described the same side effects such as blood clots, depression and liver disfunction.
What do you thinkabou that? From what I can see on their website, Progesteril contains only wild yam and soy and no hormones, bioidentical or otherwise. Unless the hormones are there but not on the ingredient list. Thank you, just one thing more — is it still pharmaceutical, isnt it? It is not make from wild yam as the progesterone creame is made. Hello Lara, just to clarify, would levonorgestrel block progesterone lower it , making cortisol high or would it increase progesterone levels overall?
Very much interested in your reply, thank you! When levonorgestrel is given in a dose sufficient to block ovulation most pills and implants , then it switches off progesterone entirely. Because ovulation is the only way to make progesterone. The levonorgestrel in the Mirena IUD is a lower dose and so does not always switch off ovulation but it sometimes does , so does not lower progesterone as much.
Let your doctor know about any allergies you have to medicine or food. Also tell your doctor if you have a family history of cancer. Be sure to go over every drug you use, including herbal supplements and over-the-counter drugs you take. Also avoid Prometrium if you are or think you might be pregnant. Because there are concerns that progesterone might increase the risk of blood clots, let your doctor know if you plan to have surgery.
You might have to stop taking the drug for about four to six weeks before your procedure. Smoking can further increase your risk for a blood clot. You should take Prometrium for the shortest length of time, and in the smallest dose, needed to treat your condition.
If you take combination hormone replacement therapy, see your doctor every three to six months to make sure you still need Prometrium. Also get regular physical exams to check your heart and overall health. What's the best and most natural way to increase your progesterone levels? We look at the pros and cons of creams, pills, foods, and more.
Progesterone is a sex hormone produced in the ovaries. Low levels of progesterone can lead to infertility, uterine bleeding, and other complications…. Secondary amenorrhea occurs when you miss your period for six months or longer. Learn about its causes, symptoms, and treatment. Chinese yam has been used for its medicinal properties for centuries. Read more about its benefits. It's especially important to care for your body during and after menopause.
This guide offers comprehensive dietary and fitness tips for menopause. There are quite a few non-hormonal treatments for vaginal dryness, such as vaginal moisturizers and vaginal lubricants.
These are the best options.
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